cefazolin time or concentration dependent

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cefazolin time or concentration dependent

由 JR Marcelin 著作 — Due to time-dependent pharmacodynamics, the efficacy of cephalosporins is associated with time above the minimum inhibitory concentration (T>MIC ... ,由 KA Cholewka 著作 · 1999 · 被引用 3 次 — Dependence of the bactericidal effect of β-lactam antibiotics in general, and cephalosporins in particular, on antibiotic concentration, time of exposure or ... ,由 BI Naik 著作 · 2017 · 被引用 33 次 — Cefazolin is a time-dependent antibiotic that demonstrates maximal efficacy when ... The observed mean (sd) total and unbound cefazolin concentration–time ... ,Cefazolin is a time-dependent antibiotic that demonstrates maximal efficacy when serum concentrations are above the minimal inhibitory concentration (MIC; ƒT>MIC). ,由 H Booke 著作 · 2021 · 被引用 3 次 — In this setting, cefazolin has a retention time of 3.16 min (see Fig. ... As PK of cefazolin is mainly dependent on renal function and CRRT ... ,由 A Douglas 著作 · 2011 · 被引用 83 次 — The median cross-clamp time of 54 min (IQR, 48 to 66 min) was not dependent upon the overall duration of surgery, which had an IQR of 2.6 to 3.2 h. ,由 P Cagnardi 著作 · 被引用 12 次 — Cephalosporins like all beta-lactams have time-dependent killing activity; therefore, antibiotic plasma concentrations should be kept above the. ,由 T Kusaba 著作 · 2009 · 被引用 40 次 — In these case reports, cefazolin was administered 3 to 8 g/day for several days despite of severe renal impairment (at least, more than 7.2 mg/ ... ,Interstitial fluid drug concentrations are proportional to and in rapid equilibrium with blood and, therefore, the concentration of the antibiotic correlates ... ,由 AA Bhalodi 著作 · 2013 · 被引用 28 次 — Similar to other cephalosporins, cefazolin displays time-dependent killing, and therefore, the PD driver of efficacy is the amount of time that free-drug ...

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cefazolin time or concentration dependent 相關參考資料
#PharmToExamTable: What is the evidence for continuous ...

由 JR Marcelin 著作 — Due to time-dependent pharmacodynamics, the efficacy of cephalosporins is associated with time above the minimum inhibitory concentration (T>MIC ...

https://blog.unmc.edu

Cephalosporin clinical concentration–time profile modelling ...

由 KA Cholewka 著作 · 1999 · 被引用 3 次 — Dependence of the bactericidal effect of β-lactam antibiotics in general, and cephalosporins in particular, on antibiotic concentration, time of exposure or ....

https://academic.oup.com

Comparative total and unbound pharmacokinetics of ...

由 BI Naik 著作 · 2017 · 被引用 33 次 — Cefazolin is a time-dependent antibiotic that demonstrates maximal efficacy when ... The observed mean (sd) total and unbound cefazolin concentration–time ...

https://www.sciencedirect.com

Comparative total and unbound pharmacokinetics of cefazolin ...

Cefazolin is a time-dependent antibiotic that demonstrates maximal efficacy when serum concentrations are above the minimal inhibitory concentration (MIC; ƒT>MIC).

https://www.bjanaesthesia.org.

Excessive unbound cefazolin concentrations in critically ill ...

由 H Booke 著作 · 2021 · 被引用 3 次 — In this setting, cefazolin has a retention time of 3.16 min (see Fig. ... As PK of cefazolin is mainly dependent on renal function and CRRT ...

https://www.nature.com

Plasma and Tissue Pharmacokinetics of Cefazolin in ...

由 A Douglas 著作 · 2011 · 被引用 83 次 — The median cross-clamp time of 54 min (IQR, 48 to 66 min) was not dependent upon the overall duration of surgery, which had an IQR of 2.6 to 3.2 h.

https://www.ncbi.nlm.nih.gov

Population Pharmacokinetic Study of Cefazolin Used ...

由 P Cagnardi 著作 · 被引用 12 次 — Cephalosporins like all beta-lactams have time-dependent killing activity; therefore, antibiotic plasma concentrations should be kept above the.

https://air.unimi.it

Safety and Efficacy of Cefazolin Sodium in the Management of ...

由 T Kusaba 著作 · 2009 · 被引用 40 次 — In these case reports, cefazolin was administered 3 to 8 g/day for several days despite of severe renal impairment (at least, more than 7.2 mg/ ...

https://journals.sagepub.com

Time-Dependent vs. Concentration-Dependent Killing

Interstitial fluid drug concentrations are proportional to and in rapid equilibrium with blood and, therefore, the concentration of the antibiotic correlates ...

http://www.antimicrobe.org

Tissue Pharmacokinetics of Cefazolin in Patients with ...

由 AA Bhalodi 著作 · 2013 · 被引用 28 次 — Similar to other cephalosporins, cefazolin displays time-dependent killing, and therefore, the PD driver of efficacy is the amount of time that free-drug ...

https://www.ncbi.nlm.nih.gov