capsaicin trpv1 desensitization
,由 B Liu 著作 · 2005 · 被引用 244 次 — The cloned vanilloid receptor TRPV1 explains most of the biological actions of capsaicin on sensory neurons, including its antinociceptive effects. Prolonged or ... ,由 DC Rosenberger 著作 · 2020 · 被引用 16 次 — Desensitizing TRPV1-expressing skin nerve fibers with capsaicin abolished laser heat pain. TRPV1-expressing HEK cells responded to laser heat ... ,由 L Luo 著作 · 2019 · 被引用 60 次 — Following heat-induced activation (Ah), TRPV1 desensitizes (Dh) rapidly (in ms-to-s time scale) if noxious heat persists. Ah has been suggested ... ,由 M Numazaki 著作 · 2003 · 被引用 412 次 — The desensitization may induce refractoriness of sensory neurons to other noxious stimuli, leading to the use of capsaicin as an analgesic agent. The Ca2+ ... ,由 MJM Fischer 著作 · 2020 · 被引用 33 次 — By contrast, TRPV1 agonists like capsaicin desensitize the whole neuron, rendering it “silent” (Figure 1). This explains why the capsaicin desensitization ... ,由 MO Petrushenko 著作 · 2020 · 被引用 7 次 — All DRG neurons demonstrating calcium responses to capsaicin could be divided into four groups, units with slow-enhancing capsaicin effects ... ,由 M Tominaga 著作 · 2006 · 被引用 4 次 — Single‐channel currents of TRPV1 evoked by three different stimuli— capsaicin, proton, or heat—suggest that TRPV1 channel is gated directly by the stimuli. ,由 L VYKLICKÝ 著作 · 2008 · 被引用 151 次 — Tentative model of TRPV1 capsaicin-induced Ca2+-dependent desensitization. The cytosolic ankyrin-repeat domain of TRPV1. (residues 101-364) binds ATP and ... ,由 OA Petrushenko 著作 · 2023 · 被引用 1 次 — Short-term sequential application of the TRPV1 channel agonist capsaicin (100nM) leads to the desensitization of TRPV1 channels by the type of tachyphylaxis. We ...
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 capsaicin trpv1 desensitization 相關參考資料
Agonist- and Ca2+-dependent Desensitization of TRPV1 ...
https://www.ncbi.nlm.nih.gov Functional Recovery from Desensitization of Vanilloid ...
由 B Liu 著作 · 2005 · 被引用 244 次 — The cloned vanilloid receptor TRPV1 explains most of the biological actions of capsaicin on sensory neurons, including its antinociceptive effects. Prolonged or .... https://www.ncbi.nlm.nih.gov The capsaicin receptor TRPV1 is the first line defense ...
由 DC Rosenberger 著作 · 2020 · 被引用 16 次 — Desensitizing TRPV1-expressing skin nerve fibers with capsaicin abolished laser heat pain. TRPV1-expressing HEK cells responded to laser heat ... https://translational-medicine Molecular basis for heat desensitization of TRPV1 ion ...
由 L Luo 著作 · 2019 · 被引用 60 次 — Following heat-induced activation (Ah), TRPV1 desensitizes (Dh) rapidly (in ms-to-s time scale) if noxious heat persists. Ah has been suggested ... https://www.nature.com Structural determinant of TRPV1 desensitization interacts ...
由 M Numazaki 著作 · 2003 · 被引用 412 次 — The desensitization may induce refractoriness of sensory neurons to other noxious stimuli, leading to the use of capsaicin as an analgesic agent. The Ca2+ ..... https://www.pnas.org The Mysteries of Capsaicin-Sensitive Afferents
由 MJM Fischer 著作 · 2020 · 被引用 33 次 — By contrast, TRPV1 agonists like capsaicin desensitize the whole neuron, rendering it “silent” (Figure 1). This explains why the capsaicin desensitization ..... https://www.frontiersin.org Activation and Desensitization of TRPV1 Channels under ...
由 MO Petrushenko 著作 · 2020 · 被引用 7 次 — All DRG neurons demonstrating calcium responses to capsaicin could be divided into four groups, units with slow-enhancing capsaicin effects ... https://link.springer.com Chapter 6 Gating, Sensitization, and Desensitization of ...
由 M Tominaga 著作 · 2006 · 被引用 4 次 — Single‐channel currents of TRPV1 evoked by three different stimuli— capsaicin, proton, or heat—suggest that TRPV1 channel is gated directly by the stimuli. https://www.sciencedirect.com Calcium-Dependent Desensitization of Vanilloid Receptor ...
由 L VYKLICKÝ 著作 · 2008 · 被引用 151 次 — Tentative model of TRPV1 capsaicin-induced Ca2+-dependent desensitization. The cytosolic ankyrin-repeat domain of TRPV1. (residues 101-364) binds ATP and ...... https://www.biomed.cas.cz Resensitization of TRPV1 channels after the P2 receptor ...
由 OA Petrushenko 著作 · 2023 · 被引用 1 次 — Short-term sequential application of the TRPV1 channel agonist capsaicin (100nM) leads to the desensitization of TRPV1 channels by the type of tachyphylaxi... https://www.frontiersin.org |