Positive-inside rule

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Positive-inside rule

According to the positive-inside rule, cytosolic loops near the lipid bilayer contain more positively-charged amino acids. Applying this rule resulted in the first topology prediction methods. ,由 JA Baker 著作 · 2017 · 被引用 100 次 — The “positive-inside rule” reported by von Heijne [2, 12] postulates the preferential occurrence of positively charged residues (lysine and ... ,由 Y Gavel 著作 · 1991 · 被引用 125 次 — We now present an analysis of proteins from the thylakoid membrane of chloroplasts. It is shown that these proteins have the same charge asymmetry as has been ... ,It's less a rule than a statistical observation. The positive inside rule is an observation made by Gunnar von Heijne where he noticed ... ,由 A Elazar 著作 · 2016 · 被引用 53 次 — The Positive-Inside Rule Can Drive Insertion of Polar Segments in Large Membrane Domains. Many transporters and receptors have membrane-embedded ... ,2014年12月8日 — Proteins insert according to the positive inside rule because positive charges tend to stay in the cytoplasm. Cells tend to have an ... ,由 G von Heijne 著作 · 1992 · 被引用 2128 次 — ... positive-inside rule. A straightforward implementation with no attempts at optimization predicts the correct topology for 23 out of 24 inner membrane ... ,According to the positive-inside rule, cytosolic loops near the lipid bilayer contain more positively-charged amino acids. Applying this rule resulted in the first topology prediction methods. ,Generally, basic residues in membrane proteins are abundant near the membrane surface on the cytoplasmic side; this is known as the positive-inside rule [33, 34] ...

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Positive-inside rule 相關參考資料
Membrane topology - Wikipedia

According to the positive-inside rule, cytosolic loops near the lipid bilayer contain more positively-charged amino acids. Applying this rule resulted in the first topology prediction methods.

https://en.wikipedia.org

Charged residues next to transmembrane regions revisited

由 JA Baker 著作 · 2017 · 被引用 100 次 — The “positive-inside rule” reported by von Heijne [2, 12] postulates the preferential occurrence of positively charged residues (lysine and ...

https://bmcbiol.biomedcentral.

The 'positive-inside rule' applies to thylakoid membrane ...

由 Y Gavel 著作 · 1991 · 被引用 125 次 — We now present an analysis of proteins from the thylakoid membrane of chloroplasts. It is shown that these proteins have the same charge asymmetry as has been ....

https://pubmed.ncbi.nlm.nih.go

For membrane proteins, what is the 'positive inside rule'?

It's less a rule than a statistical observation. The positive inside rule is an observation made by Gunnar von Heijne where he noticed ...

https://www.quora.com

Interplay between hydrophobicity and the positive-inside ...

由 A Elazar 著作 · 2016 · 被引用 53 次 — The Positive-Inside Rule Can Drive Insertion of Polar Segments in Large Membrane Domains. Many transporters and receptors have membrane-embedded ...

https://www.pnas.org

Why does the 'Positive-inside Rule' exist?

2014年12月8日 — Proteins insert according to the positive inside rule because positive charges tend to stay in the cytoplasm. Cells tend to have an ...

https://biology.stackexchange.

Membrane protein structure prediction. Hydrophobicity ...

由 G von Heijne 著作 · 1992 · 被引用 2128 次 — ... positive-inside rule. A straightforward implementation with no attempts at optimization predicts the correct topology for 23 out of 24 inner membrane ...

https://pubmed.ncbi.nlm.nih.go

Lecture 08, concept 10: Membrane protein topology - the von ...

According to the positive-inside rule, cytosolic loops near the lipid bilayer contain more positively-charged amino acids. Applying this rule resulted in the first topology prediction methods.

https://www.youtube.com

PE and the positive inside rule. A cytoplasmic domain ...

Generally, basic residues in membrane proteins are abundant near the membrane surface on the cytoplasmic side; this is known as the positive-inside rule [33, 34] ...

https://www.researchgate.net