zo-1 function

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zo-1 function

These observations suggest that one functional role of ZO-1 is to organize components of the tight junction and link them to the cortical actin cytoskeleton. ,由 E McNeil 著作 · 2006 · 被引用 301 次 — Zonula occludens (ZO)-1 was the first tight junction protein to be cloned and has been implicated as an important scaffold protein. ,2015年3月9日 — We demonstrate that the tight junction protein ZO-1 regulates tension acting on VE-cadherin–based adherens junctions, cell migration, and barrier formation. ,It has a role as a scaffold protein which cross-links and anchors Tight Junction (TJ) strand proteins, which are fibril-like structures within the lipid bilayer ... ,由 WT Kuo 著作 · 2021 · 被引用 239 次 — ZO-1 is essential for mucosal repair. We speculate that ZO-1 down-regulation may be one cause of ineffective mucosal healing in patients with IBD. ,The ZO proteins (ZO-1, ZO-2 and ZO-3) are cytosolic scaffolding proteins that regulate the assembly of multiple proteins at the intercellular tight junctions. ,由 AJ Haas 著作 · 2022 · 被引用 28 次 — A central role in the regulation of mechanosensation and force transmission at TJ is played by ZO-1, a multidomain cytosolic protein of the MAGUK family that ... ,The tight junction acts to limit movement of substances through the paracellular space and as a boundary between the compositionally distinct apical and ... ,由 AS Fanning 著作 · 1998 · 被引用 1778 次 — We suggest that ZO-1 forms a functional link between the paracellular seal and the actin cytoskeleton.,由 CM Van Itallie 著作 · 2009 · 被引用 496 次 — ZO-1 limits solute permeability in established tight junctions, perhaps by forming a stabilizing link between the barrier and perijunctional actomyosin.

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zo-1 function 相關參考資料
The tight junction protein ZO-1 establishes a link ... - PubMed

These observations suggest that one functional role of ZO-1 is to organize components of the tight junction and link them to the cortical actin cytoskeleton.

https://pubmed.ncbi.nlm.nih.go

Zonula Occludens-1 Function in the Assembly of Tight ...

由 E McNeil 著作 · 2006 · 被引用 301 次 — Zonula occludens (ZO)-1 was the first tight junction protein to be cloned and has been implicated as an important scaffold protein.

https://www.ncbi.nlm.nih.gov

ZO-1 controls endothelial adherens junctions, cell ...

2015年3月9日 — We demonstrate that the tight junction protein ZO-1 regulates tension acting on VE-cadherin–based adherens junctions, cell migration, and barrier formation.

https://rupress.org

Tight junction protein ZO-1

It has a role as a scaffold protein which cross-links and anchors Tight Junction (TJ) strand proteins, which are fibril-like structures within the lipid bilayer ...

https://en.wikipedia.org

The Tight Junction Protein ZO-1 Is Dispensable for Barrier ...

由 WT Kuo 著作 · 2021 · 被引用 239 次 — ZO-1 is essential for mucosal repair. We speculate that ZO-1 down-regulation may be one cause of ineffective mucosal healing in patients with IBD.

https://www.gastrojournal.org

Protein ZO1 - an overview

The ZO proteins (ZO-1, ZO-2 and ZO-3) are cytosolic scaffolding proteins that regulate the assembly of multiple proteins at the intercellular tight junctions.

https://www.sciencedirect.com

ZO-1 Guides Tight Junction Assembly and Epithelial ...

由 AJ Haas 著作 · 2022 · 被引用 28 次 — A central role in the regulation of mechanosensation and force transmission at TJ is played by ZO-1, a multidomain cytosolic protein of the MAGUK family that ......

https://www.mdpi.com

TJP1 - Tight junction protein ZO-1 - Homo sapiens (Human)

The tight junction acts to limit movement of substances through the paracellular space and as a boundary between the compositionally distinct apical and ...

https://www.uniprot.org

The Tight Junction Protein ZO-1 Establishes a Link ...

由 AS Fanning 著作 · 1998 · 被引用 1778 次 — We suggest that ZO-1 forms a functional link between the paracellular seal and the actin cytoskeleton.

https://www.sciencedirect.com

ZO-1 Stabilizes the Tight Junction Solute Barrier through ...

由 CM Van Itallie 著作 · 2009 · 被引用 496 次 — ZO-1 limits solute permeability in established tight junctions, perhaps by forming a stabilizing link between the barrier and perijunctional actomyosin.

https://www.molbiolcell.org