what part of the cell cycle does the prb protein h

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what part of the cell cycle does the prb protein h

由 C Uchida 著作 · 2016 · 被引用 45 次 — Retinoblastoma protein (pRB) was the first identified tumor suppressor that negatively regulates the G0/G1 to S phase transition of the cell ... ,One function of pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide. When the cell is ready to divide, ... ,The retinoblastoma protein (pRB) was the first tumor suppressor to be discovered, and it regulates the G1 to S phase transition at the beginning of the cell cycle. Deregulation of cell cycle control in cancer requires inactivation of this growth regulator,由 K Engeland 著作 · 2022 · 被引用 573 次 — The retinoblastoma protein RB and the transcription factor p53 are central tumor suppressors. They are often found inactivated in various tumor types. ,由 MM Kasten 著作 · 1998 · 被引用 155 次 — The retinoblastoma protein, pRb, acts to connect the cell cycle to the transcriptional machinery primarily by binding to the E2F transcription factors, ...,由 EA Harrington 著作 · 1998 · 被引用 308 次 — pRB is one member of a family of structurally and functionally conserved proteins that play a key role in negative regulation of the cell cycle via binding to ...,由 L Zhou 著作 · 2022 · 被引用 28 次 — The retinoblastoma protein (pRb) functions as a cell cycle regulator controlling G1 to S phase transition and plays critical roles in tumour ... ,The most well-characterized function of pRB is its ability to repress E2F-dependent transcription at the G1/S transition of the cell cycle, though this is only ... ,由 BE Engel 著作 · 2015 · 被引用 50 次 — This review will highlight pRb's role in the control of cell adhesion and how alterations in the adhesive properties of tumor cells may drive the deadly ... ,由 GU Höglinger 著作 · 2007 · 被引用 326 次 — The S phase is typically initiated by phosphorylation of pRb, leading to the release of E2F transcription factors. Unbound E2F proteins autoinduce E2F gene ...

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what part of the cell cycle does the prb protein h 相關參考資料
Roles of pRB in the Regulation of Nucleosome and ...

由 C Uchida 著作 · 2016 · 被引用 45 次 — Retinoblastoma protein (pRB) was the first identified tumor suppressor that negatively regulates the G0/G1 to S phase transition of the cell ...

https://onlinelibrary.wiley.co

Retinoblastoma protein

One function of pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide. When the cell is ready to divide, ...

https://en.wikipedia.org

Regulation of transcription and chromatin structure by pRB

The retinoblastoma protein (pRB) was the first tumor suppressor to be discovered, and it regulates the G1 to S phase transition at the beginning of the cell cycle. Deregulation of cell cycle control i...

https://www.ncbi.nlm.nih.gov

Cell cycle regulation: p53-p21-RB signaling

由 K Engeland 著作 · 2022 · 被引用 573 次 — The retinoblastoma protein RB and the transcription factor p53 are central tumor suppressors. They are often found inactivated in various tumor types.

https://www.nature.com

pRb and the Cdks in apoptosis and the cell cycle

由 MM Kasten 著作 · 1998 · 被引用 155 次 — The retinoblastoma protein, pRb, acts to connect the cell cycle to the transcriptional machinery primarily by binding to the E2F transcription factors, ...

https://www.nature.com

pRB plays an essential role in cell cycle arrest induced ...

由 EA Harrington 著作 · 1998 · 被引用 308 次 — pRB is one member of a family of structurally and functionally conserved proteins that play a key role in negative regulation of the cell cycle via bindin...

https://www.pnas.org

Post-translational modifications on the retinoblastoma protein

由 L Zhou 著作 · 2022 · 被引用 28 次 — The retinoblastoma protein (pRb) functions as a cell cycle regulator controlling G1 to S phase transition and plays critical roles in tumour ...

https://jbiomedsci.biomedcentr

Retinoblastoma Protein - an overview

The most well-characterized function of pRB is its ability to repress E2F-dependent transcription at the G1/S transition of the cell cycle, though this is only ...

https://www.sciencedirect.com

THE RETINOBLASTOMA PROTEIN: A MASTER TUMOR ...

由 BE Engel 著作 · 2015 · 被引用 50 次 — This review will highlight pRb's role in the control of cell adhesion and how alterations in the adhesive properties of tumor cells may drive the deadly ...

https://www.ncbi.nlm.nih.gov

The pRbE2F cell-cycle pathway mediates cell death in ...

由 GU Höglinger 著作 · 2007 · 被引用 326 次 — The S phase is typically initiated by phosphorylation of pRb, leading to the release of E2F transcription factors. Unbound E2F proteins autoinduce E2F gene...

https://www.pnas.org