ptz drug

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ptz drug

Although animal models based on pentylenetetrazole (PTZ) are widely used, the ... on PTZ-induced clonic seizures in drug naive and PTZ-kindled mice as well ... ,Furthermore, TID50 (the dose of an anticonvulsant drug required to increase the PTZ seizure threshold for tonic extensor by 50%) was calculated for all drugs, and ... ,The results indicate that PTZ acts via the cell membrane and influences the membrane-associated part of the potassium channel. Thereby, PTZ accelerates the ... ,PTZ induces all four behavioral phenomena – freezing, myoclonic twitches, clonic ... focus as a diagnostic procedure in patients with drug-resistant epilepsy [3]. ,Pentylenetetrazol (PTZ)-induced seizure in rats, a relevant model of human ... Tested Molecules, Ages, Drug Administration; Seizure Induction Method, Results ... ,Pentylenetetrazol, also known as pentylenetetrazole, metrazol, pentetrazol (INN), pentamethylenetetrazol, Corazol, Cardiazol, deumacard or PTZ, is a drug formerly used as a circulatory and respiratory stimulant. ,Pentylenetetrazole (PTZ) is a central nervous system modulator that is used to ... and some drugs that block PTZ-induced seizures, including benzodiazepines, ... ,Development of Neurosteroid-Based Novel Psychotropic Drugs ... are able to protect against pentylenetetrazole (PTZ)-induced seizures in animais as are the ... ,In rats, in addition to evaluating drug effects on generalized clonic seizures, ... Tonic seizures induced by PTZ were blocked by drugs, such as ethosuximide, ...

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ptz drug 相關參考資料
Anticonvulsant and antiepileptogenic effects of GABAA ...

Although animal models based on pentylenetetrazole (PTZ) are widely used, the ... on PTZ-induced clonic seizures in drug naive and PTZ-kindled mice as well ...

https://pubmed.ncbi.nlm.nih.go

Effect of various antiepileptic drugs in a pentylenetetrazol ...

Furthermore, TID50 (the dose of an anticonvulsant drug required to increase the PTZ seizure threshold for tonic extensor by 50%) was calculated for all drugs, and ...

https://pubmed.ncbi.nlm.nih.go

Mechanism of action of the epileptogenic drug ... - PubMed

The results indicate that PTZ acts via the cell membrane and influences the membrane-associated part of the potassium channel. Thereby, PTZ accelerates the ...

https://pubmed.ncbi.nlm.nih.go

Pentetrazole - an overview | ScienceDirect Topics

PTZ induces all four behavioral phenomena – freezing, myoclonic twitches, clonic ... focus as a diagnostic procedure in patients with drug-resistant epilepsy [3].

https://www.sciencedirect.com

Pentylenetetrazol - an overview | ScienceDirect Topics

Pentylenetetrazol (PTZ)-induced seizure in rats, a relevant model of human ... Tested Molecules, Ages, Drug Administration; Seizure Induction Method, Results ...

https://www.sciencedirect.com

Pentylenetetrazol - Wikipedia

Pentylenetetrazol, also known as pentylenetetrazole, metrazol, pentetrazol (INN), pentamethylenetetrazol, Corazol, Cardiazol, deumacard or PTZ, is a drug formerly used as a circulatory and respiratory...

https://en.wikipedia.org

Pentylenetetrazole (α,β-Cyclopentamethylenetetrazole, 1,5 ...

Pentylenetetrazole (PTZ) is a central nervous system modulator that is used to ... and some drugs that block PTZ-induced seizures, including benzodiazepines, ...

https://www.caymanchem.com

Pentylenetetrazole-Induced Seizure - an overview ...

Development of Neurosteroid-Based Novel Psychotropic Drugs ... are able to protect against pentylenetetrazole (PTZ)-induced seizures in animais as are the ...

https://www.sciencedirect.com

The role of technical, biological and pharmacological factors ...

In rats, in addition to evaluating drug effects on generalized clonic seizures, ... Tonic seizures induced by PTZ were blocked by drugs, such as ethosuximide, ...

https://pubmed.ncbi.nlm.nih.go