ikr channel

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ikr channel

hERG is a gene (KCNH2) that codes for a protein known as Kv11.1, the alpha subunit of a ... This ion channel (sometimes simply denoted as 'hERG') is best known for its contribution to the electrical activity of the heart: the hERG channel mediates,hERG (the human Ether-à-go-go-Related Gene),是指基因KCNH2。該基因編碼的蛋白質被稱為Kv11.1,是鉀離子通道(英語:potassium ion channel)的α亞基( ... ,There have been extensive efforts to develop I(Kr) channel blockers as a new antiarrhythmic agent for atrial or ventricular fibrillation, since it was demonstrated ... ,The rapid delayed rectifier (IKr) channel is important for cardiac action potential repolarization. Suppressing IKr function, due to either genetic defects in its pore- ... ,2011年10月7日 — ... (IKr) and slowly (IKs) activating delayed rectifier potassium channels ... the mature hERG channel expression but had no effect on KCNQ1. ,(IKr, IKs, IKur) and inward flow of current through L-type. Ca2+ channels. The rate of terminal repolarization (phase. 3) is enhanced after the plateau phase ... ,channels (ICaL) are balanced by the different components of the delayed rectifier K+ current (IKur, IKr and IKs). The terminal phase 3 of repolarization is due to ... ,Human ether-a-go-go-related gene (hERG) potassium channels conduct the rapid component of the delayed rectifier potassium current, IKr, which is crucial for ...

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ikr channel 相關參考資料
hERG - Wikipedia

hERG is a gene (KCNH2) that codes for a protein known as Kv11.1, the alpha subunit of a ... This ion channel (sometimes simply denoted as 'hERG') is best known for its contribution to the elec...

https://en.wikipedia.org

hERG - 維基百科,自由的百科全書 - Wikipedia

hERG (the human Ether-à-go-go-Related Gene),是指基因KCNH2。該基因編碼的蛋白質被稱為Kv11.1,是鉀離子通道(英語:potassium ion channel)的α亞基( ...

https://zh.wikipedia.org

IKr channel blockers: novel antiarrhythmic agents - PubMed

There have been extensive efforts to develop I(Kr) channel blockers as a new antiarrhythmic agent for atrial or ventricular fibrillation, since it was demonstrated ...

https://pubmed.ncbi.nlm.nih.go

IKr: The hERG Channel - ScienceDirect

The rapid delayed rectifier (IKr) channel is important for cardiac action potential repolarization. Suppressing IKr function, due to either genetic defects in its pore- ...

https://www.sciencedirect.com

Interaction between the cardiac rapidly (IKr) and slowly (IKs ...

2011年10月7日 — ... (IKr) and slowly (IKs) activating delayed rectifier potassium channels ... the mature hERG channel expression but had no effect on KCNQ1.

https://pubmed.ncbi.nlm.nih.go

Molecular Biology of K Channels and Their Role in Cardiac ...

(IKr, IKs, IKur) and inward flow of current through L-type. Ca2+ channels. The rate of terminal repolarization (phase. 3) is enhanced after the plateau phase ...

https://www.amjmed.com

Pharmacology of cardiac potassium channels

channels (ICaL) are balanced by the different components of the delayed rectifier K+ current (IKur, IKr and IKs). The terminal phase 3 of repolarization is due to ...

https://academic.oup.com

The cardiac hERGIKr potassium channel as pharmacological ...

Human ether-a-go-go-related gene (hERG) potassium channels conduct the rapid component of the delayed rectifier potassium current, IKr, which is crucial for ...

https://pubmed.ncbi.nlm.nih.go