cyclin b
Cyclin B is a member of the cyclin family. Cyclin B is a mitotic cyclin. The amount of cyclin B (which binds to Cdk1) and the activity of the cyclin B-Cdk complex rise through the cell cycle until mitosis, where they fall abruptly due to degradation of cy,G2/mitotic-specific cyclin-B1 is a protein that in humans is encoded by the CCNB1 gene. Contents. [hide]. 1 Function; 2 Regulation; 3 Interactions; 4 Cancer. 4.1 Down regulation and tumor suppression; 4.2 Tumor antigen; 4.3 Breast cancer; 4.4 Lung cancer.,例如：cyclin D活化CDK4或CDK6掌控G1期的細胞生長；cyclin A及cyclin E活化CDK2調控染色體複製；cyclin A及cyclin B活化CDK1調控有絲分裂和減數分裂。有趣的是，有些週期素雖然擁有cyclin box但它們沒有可活化的CDK：例如cyclin F, cyclin I以及cyclin G。而且cyclin I並沒有細胞週期的調控功能，它主要作用在神經細胞上。 ,CDK1-cyclin B (Cyclin Dependent Kinase 1), also known as Cdc2-cyclin B (Cell division control protein kinase 2) or M-phase promoting factor (MPF), is a member of cyclin-dependent kinases implicated in cell cycle control in eukaryotes. Activation of the CD,During mitosis active Cdk1–cyclin B–Cks phosphorylates key substrates leading to dramatic reorganization of the cell and, ultimately, to separation of sister chromatids on the mitotic spindle. Once chromatids are separated, the cell must return to a state,The degradation of the cyclin B subunit of protein kinase Cdk1/cyclin B is required for inactivation of the kinase and exit from mitosis. Cyclin B is degraded by the ubiquitin pathway, a system involved in most selective protein degradation in eukaryotic ,Philos Trans R Soc Lond B Biol Sci. 1999 Sep 29;354(1389):1571-5; discussion 1575-6. Mechanisms and regulation of the degradation of cyclin B. Hershko A(1). Author information: (1)Unit of Biochemistry, B. Rappaport Faculty of Medicine, Technion-Israel Ins, We identified the known APC/C regulator Cdh1 and the F-box protein Fbxl15 as specific modulators of N-cyclin B1-luciferase steady-state levels and turnover. Collectively, our studies suggest that analyzing the steady-state levels of luciferase fusion pro,cyclin B1 Antibody (GNS1) is a high quality mouse monoclonal recommended for detecting cyclin B1 of mouse, rat and human origin by WB, IP, KA, IF and IHC(P) ,Polyclonal Antibody for studying Cyclin B1 in the Cell Cycle / Checkpoint research area.
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 cyclin b 相關參考資料
Cyclin B - Wikipedia
Cyclin B is a member of the cyclin family. Cyclin B is a mitotic cyclin. The amount of cyclin B (which binds to Cdk1) and the activity of the cyclin B-Cdk complex rise through the cell cycle until mit... https://en.wikipedia.org Cyclin B1 - Wikipedia
G2/mitotic-specific cyclin-B1 is a protein that in humans is encoded by the CCNB1 gene. Contents. [hide]. 1 Function; 2 Regulation; 3 Interactions; 4 Cancer. 4.1 Down regulation and tumor suppression;... https://en.wikipedia.org 週期素- 維基百科，自由的百科全書 - Wikipedia
例如：cyclin D活化CDK4或CDK6掌控G1期的細胞生長；cyclin A及cyclin E活化CDK2調控染色體複製；cyclin A及cyclin B活化CDK1調控有絲分裂和減數分裂。有趣的是，有些週期素雖然擁有cyclin box但它們沒有可活化的CDK：例如cyclin F, cyclin I以及cyclin G。而且cyclin I並沒有細胞週期的調控功能，它主要作用在神經細胞... https://zh.wikipedia.org CDK1-cyclin B | NEB
CDK1-cyclin B (Cyclin Dependent Kinase 1), also known as Cdc2-cyclin B (Cell division control protein kinase 2) or M-phase promoting factor (MPF), is a member of cyclin-dependent kinases implicated in... https://www.neb.com Cyclin B - an overview | ScienceDirect Topics
During mitosis active Cdk1–cyclin B–Cks phosphorylates key substrates leading to dramatic reorganization of the cell and, ultimately, to separation of sister chromatids on the mitotic spindle. Once ch... https://www.sciencedirect.com Mechanisms and regulation of the degradation of cyclin B. - NCBI - NIH
The degradation of the cyclin B subunit of protein kinase Cdk1/cyclin B is required for inactivation of the kinase and exit from mitosis. Cyclin B is degraded by the ubiquitin pathway, a system involv... https://www.ncbi.nlm.nih.gov Mechanisms and regulation of the degradation of cyclin B. - NCBI
Philos Trans R Soc Lond B Biol Sci. 1999 Sep 29;354(1389):1571-5; discussion 1575-6. Mechanisms and regulation of the degradation of cyclin B. Hershko A(1). Author information: (1)Unit of Biochemistry... https://www.ncbi.nlm.nih.gov CCNB1 cyclin B1 [ (human)] - NCBI
We identified the known APC/C regulator Cdh1 and the F-box protein Fbxl15 as specific modulators of N-cyclin B1-luciferase steady-state levels and turnover. Collectively, our studies suggest that ana... https://www.ncbi.nlm.nih.gov cyclin B1 Antibody (GNS1) | SCBT - Santa Cruz Biotechnology
cyclin B1 Antibody (GNS1) is a high quality mouse monoclonal recommended for detecting cyclin B1 of mouse, rat and human origin by WB, IP, KA, IF and IHC(P) https://www.scbt.com CST - Cyclin B1 Antibody
Polyclonal Antibody for studying Cyclin B1 in the Cell Cycle / Checkpoint research area. https://www.cellsignal.com |