b catenin cancer
As β-catenin is the central player of the canonical Wnt signaling and is frequently mutated in cancers, it is the most attractive target for cancer ..., Uncontrolled expression of β-catenin is known to drive multiple types of cancers, including colon cancer, hepatocellular carcinoma and ..., ,Since its discovery as a protein associated with the cytoplasmic region of E-cadherin, beta-catenin has been shown to perform two apparently unrelated ... , Importantly, the inhibition of Wnt signaling occurred downstream of β-catenin, encouraging applications in treatment of cancers caused by APC ..., Mutations of canonical Wnt signaling pathway genes frequently occur in cancer and lead to abnormal accumulation of the key effector β-catenin ..., Colorectal cancers show evidence of Wnt signaling pathway activation ... Keywords: Wnt, beta-catenin, colorectal cancers, gamma secretase, ..., The Wnt/beta-catenin pathway is a family of proteins that is implicated in many vital cellular functions such as stem cell regeneration and ..., INTRODUCTION. β-Catenin is a multifunctional protein with a central role in physiological homeostasis. Its aberrant high expression leads to various diseases including cancer. ... Upon Wnt activation or genetic mutations of Wnt components, β-catenin accu, The β-catenin destruction complex. Colorectal cancer (CRC) is the representative of human cancer caused by Wnt signaling hyperactivation.
| 相關軟體 Polarity 資訊 | |
|---|---|
 b catenin cancer 相關參考資料
A PROTAC peptide induces durable β-catenin degradation ...
As β-catenin is the central player of the canonical Wnt signaling and is frequently mutated in cancers, it is the most attractive target for cancer ... https://www.nature.com Allosteric inhibitor of β-catenin selectively targets oncogenic ...
Uncontrolled expression of β-catenin is known to drive multiple types of cancers, including colon cancer, hepatocellular carcinoma and ... https://www.nature.com Beta-catenin - Wikipedia
https://en.wikipedia.org beta-catenin signaling and cancer - PubMed - NIH
Since its discovery as a protein associated with the cytoplasmic region of E-cadherin, beta-catenin has been shown to perform two apparently unrelated ... https://pubmed.ncbi.nlm.nih.go Cancer cell specific inhibition of Wntβ-catenin signaling by ...
Importantly, the inhibition of Wnt signaling occurred downstream of β-catenin, encouraging applications in treatment of cancers caused by APC ... https://www.nature.com Is β-Catenin a Druggable Target for Cancer Therapy?: Trends ...
Mutations of canonical Wnt signaling pathway genes frequently occur in cancer and lead to abnormal accumulation of the key effector β-catenin ... https://www.cell.com Targeting the Wntbeta-catenin Pathway in Cancer ... - NCBI
Colorectal cancers show evidence of Wnt signaling pathway activation ... Keywords: Wnt, beta-catenin, colorectal cancers, gamma secretase, ... https://www.ncbi.nlm.nih.gov Targeting the Wntbeta-catenin pathway in cancer ... - PubMed
The Wnt/beta-catenin pathway is a family of proteins that is implicated in many vital cellular functions such as stem cell regeneration and ... https://pubmed.ncbi.nlm.nih.go The regulation of β-catenin activity and function in cancer - NCBI
INTRODUCTION. β-Catenin is a multifunctional protein with a central role in physiological homeostasis. Its aberrant high expression leads to various diseases including cancer. ... Upon Wnt activation... https://www.ncbi.nlm.nih.gov Wnt signaling in cancer: therapeutic targeting of Wnt signaling ...
The β-catenin destruction complex. Colorectal cancer (CRC) is the representative of human cancer caused by Wnt signaling hyperactivation. https://www.nature.com |