TGF-beta cancer

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TGF-beta cancer

2019年8月1日 — Targeting TGF-beta signaling in cancer. Trends ... E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression. ,TGF-beta inhibits proliferation and induces apoptosis in various cell types, and accumulation of loss-of-function mutations in the TGF-beta receptor or Smad genes ... ,Abstract. Transforming growth factor beta (TGF-beta) is an effective and ubiquitous mediator of cell growth. The significance of this cytokine in cancer susceptibility ... ,The transforming growth factor (TGF)-β signaling pathway is deregulated in many diseases, including cancer. In healthy cells and early-stage cancer cells,. ,TGF-β is an important regulatory tumor suppressor factor in epithelial cells, where it early inhibits proliferation and induces apoptosis. However, tumor cells ... ,The transforming growth factor-β (TGF-β) is a family of structurally related proteins that comprises of TGF-β, activins/inhibins, and bone morphogenic proteins ... ,Abstract. The transforming growth factor β (TGFβ) signaling pathway is a key player in metazoan biology, and its misregulation can result in tumor development. ,2017年11月6日 — It is generally accepted that TGF-β is primarily a tumor suppressor in premalignant cells but functions as a promoter of metastasis in cancer cells ( ... ,TGF-β protein has dual functions on tumorigenesis where it exhibits a suppressive role by inducing cell cycle arrest and apoptosis at early stages of tumor ... ,Transforming growth factor-beta (TGF-beta) is a multifunctional regulatory polypeptide that is the prototypical member of a large family of cytokines that controls ...

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TGF-beta cancer 相關參考資料
A New Switch for TGFβ in Cancer | Cancer Research

2019年8月1日 — Targeting TGF-beta signaling in cancer. Trends ... E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression.

https://cancerres.aacrjournals

Actions of TGF-beta as tumor suppressor and pro-metastatic ...

TGF-beta inhibits proliferation and induces apoptosis in various cell types, and accumulation of loss-of-function mutations in the TGF-beta receptor or Smad genes ...

https://pubmed.ncbi.nlm.nih.go

Role of transforming growth factor beta in cancer - PubMed - NIH

Abstract. Transforming growth factor beta (TGF-beta) is an effective and ubiquitous mediator of cell growth. The significance of this cytokine in cancer susceptibility ...

https://pubmed.ncbi.nlm.nih.go

Targeting TGF-β Signaling in Cancer - Cell Press

The transforming growth factor (TGF)-β signaling pathway is deregulated in many diseases, including cancer. In healthy cells and early-stage cancer cells,.

https://www.cell.com

TGF-beta signaling in cancer treatment - PubMed

TGF-β is an important regulatory tumor suppressor factor in epithelial cells, where it early inhibits proliferation and induces apoptosis. However, tumor cells ...

https://pubmed.ncbi.nlm.nih.go

TGF-β Signaling in Cancer - PubMed

The transforming growth factor-β (TGF-β) is a family of structurally related proteins that comprises of TGF-β, activins/inhibins, and bone morphogenic proteins ...

https://pubmed.ncbi.nlm.nih.go

TGFβ in Cancer - NCBI - NIH

Abstract. The transforming growth factor β (TGFβ) signaling pathway is a key player in metazoan biology, and its misregulation can result in tumor development.

https://www.ncbi.nlm.nih.gov

TGF‑β signaling: A complex role in tumorigenesis (Review)

2017年11月6日 — It is generally accepted that TGF-β is primarily a tumor suppressor in premalignant cells but functions as a promoter of metastasis in cancer cells ( ...

https://www.spandidos-publicat

The role of TGF-βSMAD4 signaling in cancer

TGF-β protein has dual functions on tumorigenesis where it exhibits a suppressive role by inducing cell cycle arrest and apoptosis at early stages of tumor ...

https://www.ijbs.com

Transforming growth factor-beta in cancer and metastasis

Transforming growth factor-beta (TGF-beta) is a multifunctional regulatory polypeptide that is the prototypical member of a large family of cytokines that controls ...

https://pubmed.ncbi.nlm.nih.go