Immune checkpoint activation

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Immune checkpoint activation

,Immune checkpoints are regulators of the immune system. These pathways are crucial for self-tolerance, which prevents the immune system from attacking cells ... ,由 X He 著作 · 2020 · 被引用 116 次 — Inhibitory functions of immune checkpoints are tightly regulated by surface expression level, receptor-ligand interactions, and intracellular ... ,由 AD Waldman 著作 · 2020 · 被引用 528 次 — Several evolutionarily conserved negative regulators of T cell activation act as 'checkpoint molecules' to fine-tune the immune response and ... ,由 JA Marin-Acevedo 著作 · 2018 · 被引用 398 次 — In cancer, immune checkpoint pathways are often activated to inhibit the nascent anti-tumor immune response. Immune checkpoint therapies act ... ,A type of drug that blocks proteins called checkpoints that are made by some types of immune system cells, such as T cells, and some cancer cells. ,由 S Qin 著作 · 2019 · 被引用 301 次 — Recent studies have identified several new immune checkpoint targets, like lymphocyte activation gene-3 (LAG-3), T cell immunoglobulin and mucin ... ,由 R Zappasodi 著作 · 2018 · 被引用 307 次 — ... facilitate immune activation significantly extends survival of advanced cancer patients. The successes of immune checkpoint blockade, ... ,由 SC Wei 著作 · 2018 · 被引用 1296 次 — Immune checkpoint blockade removes inhibitory signals of T-cell activation, which enables tumor-reactive T cells to overcome regulatory ... ,Although these early hypotheses fueled the field of cancer immunotherapy, better understanding of immune activation, regulation, and interaction with tumor ...

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Immune checkpoint activation 相關參考資料
Immune Checkpoint Signaling Pathway - Creative Diagnostics

https://www.creative-diagnosti

Immune checkpoint - Wikipedia

Immune checkpoints are regulators of the immune system. These pathways are crucial for self-tolerance, which prevents the immune system from attacking cells ...

https://en.wikipedia.org

Immune checkpoint signaling and cancer immunotherapy

由 X He 著作 · 2020 · 被引用 116 次 — Inhibitory functions of immune checkpoints are tightly regulated by surface expression level, receptor-ligand interactions, and intracellular ...

https://www.nature.com

A guide to cancer immunotherapy: from T cell basic science

由 AD Waldman 著作 · 2020 · 被引用 528 次 — Several evolutionarily conserved negative regulators of T cell activation act as 'checkpoint molecules' to fine-tune the immune response and ...

https://www.nature.com

Next generation of immune checkpoint therapy in cancer

由 JA Marin-Acevedo 著作 · 2018 · 被引用 398 次 — In cancer, immune checkpoint pathways are often activated to inhibit the nascent anti-tumor immune response. Immune checkpoint therapies act ...

https://jhoonline.biomedcentra

Definition of immune checkpoint inhibitor - NCI Dictionary of ...

A type of drug that blocks proteins called checkpoints that are made by some types of immune system cells, such as T cells, and some cancer cells.

https://www.cancer.gov

Novel immune checkpoint targets: moving beyond PD-1 and ...

由 S Qin 著作 · 2019 · 被引用 301 次 — Recent studies have identified several new immune checkpoint targets, like lymphocyte activation gene-3 (LAG-3), T cell immunoglobulin and mucin ...

https://molecular-cancer.biome

Emerging concepts for immune checkpoint blockade-based ...

由 R Zappasodi 著作 · 2018 · 被引用 307 次 — ... facilitate immune activation significantly extends survival of advanced cancer patients. The successes of immune checkpoint blockade, ...

https://www.ncbi.nlm.nih.gov

Fundamental Mechanisms of Immune Checkpoint Blockade ...

由 SC Wei 著作 · 2018 · 被引用 1296 次 — Immune checkpoint blockade removes inhibitory signals of T-cell activation, which enables tumor-reactive T cells to overcome regulatory ...

https://cancerdiscovery.aacrjo

Mechanisms of Resistance to Immune Checkpoint Blockade

Although these early hypotheses fueled the field of cancer immunotherapy, better understanding of immune activation, regulation, and interaction with tumor ...

https://ascopubs.org