Decitabine

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Decitabine

Decitabine, sold under the brand name Dacogen, acts as a nucleic acid synthesis inhibitor. ... It is a medication for the treatment of myelodysplastic syndromes, ... ,由 E Jabbour 著作 · 2008 · 被引用 188 次 — Decitabine (5-aza-2′-deoxycytidine) is a hypomethylating agent with a dual mechanism of action: reactivation of silenced genes and differentiation at low ... ,Drug Type: Decitabine is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug. Decitabine is classified as an antimetabolite and a  ... ,由 B Hackanson 著作 · 2014 · 被引用 37 次 — Besides 5-azacytidine (azacitidine, Vidaza®), 5-aza-2'-deoxycytidine (decitabine, Dacogen®) is the most widely used inhibitor of DNA methylation, ... ,由 X Feng 著作 · 2019 · 被引用 3 次 — However, the application of decitabine in myelodysplastic syndromes (MDSs) and acute myeloid leukemia (AML) has not been fully examined. Thus, our study aimed ... ,Decitabine is a chemotherapeutic pyrimidine nucleoside analogue used for the treatment of myelodysplastic syndromes (MDS) by inducing DNA hypomethylation ... ,In preclinical studies in mice and rats, decitabine was teratogenic, fetotoxic, and embryotoxic. If this drug is used during pregnancy, or if a patient becomes ... ,Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in ...

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Decitabine 相關參考資料
Decitabine - Wikipedia

Decitabine, sold under the brand name Dacogen, acts as a nucleic acid synthesis inhibitor. ... It is a medication for the treatment of myelodysplastic syndromes, ...

https://en.wikipedia.org

Evolution of Decitabine Development - NCBI

由 E Jabbour 著作 · 2008 · 被引用 188 次 — Decitabine (5-aza-2′-deoxycytidine) is a hypomethylating agent with a dual mechanism of action: reactivation of silenced genes and differentiation at low ...

https://www.ncbi.nlm.nih.gov

Decitabine - Drug Information - Chemocare

Drug Type: Decitabine is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug. Decitabine is classified as an antimetabolite and a  ...

https://chemocare.com

Decitabine - PubMed

由 B Hackanson 著作 · 2014 · 被引用 37 次 — Besides 5-azacytidine (azacitidine, Vidaza®), 5-aza-2'-deoxycytidine (decitabine, Dacogen®) is the most widely used inhibitor of DNA methylation, ...

https://pubmed.ncbi.nlm.nih.go

Decitabine: An effective and safe treatment for ... - PubMed

由 X Feng 著作 · 2019 · 被引用 3 次 — However, the application of decitabine in myelodysplastic syndromes (MDSs) and acute myeloid leukemia (AML) has not been fully examined. Thus, our study aimed ...

https://pubmed.ncbi.nlm.nih.go

Decitabine: Uses, Interactions, Mechanism of Action - DrugBank

Decitabine is a chemotherapeutic pyrimidine nucleoside analogue used for the treatment of myelodysplastic syndromes (MDS) by inducing DNA hypomethylation ...

https://go.drugbank.com

DACOGEN® (decitabine) for injection, for intravenous use

In preclinical studies in mice and rats, decitabine was teratogenic, fetotoxic, and embryotoxic. If this drug is used during pregnancy, or if a patient becomes ...

https://www.accessdata.fda.gov

Decitabine (5-Aza-2'-deoxycytidine) | DNMT Inhibitor

Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in ...

https://www.medchemexpress.com