VLC Media Player (64-bit) 歷史版本列表
更新時間：2020-11-07
更新細節：
What's new in this version:
Fixed:
- Improved stability when dragging out selections while viewing an alignment to a reference sequence
- Sped up loading files with extensive histories
- Improved the keyboard shortcut for "Find Similar DNA Sequences" on Windows and Linux
- Corrected an issue that made it difficult to switch to compact mode in protein sequences
- Corrected an issue with updating map and sequence colors when changing the color mode
- Improved the responsiveness of cloning dialogs
- Made various stability improvements
- Corrected an issue with the software updater on macOS
更新時間：2020-10-30
更新細節：
What's new in this version:
- This version fixes various regressions and improves stability
更新時間：2020-10-14
更新細節：
What's new in this version:
New Functionality:
- Enabled visualization of GC content as a color plot in Map view or base colors in Sequence view
- Added support for finding similar DNA sequences with mismatches or indels compared to the search query
- Added support for simulating the migration of supercoiled DNA molecules in agarose gels using TBE, TAE or SB buffer
- Added support for single-stranded DNA (ssDNA) sequences
- Enabled import of Sequencher project files (*.spf)
- Enabled "Undo" for edits in large sequences
- Added DNA ladders from DyneBio
- Added supercoiled MW markers from ELPIS BIOTECH and New England Biolabs
- Added BsmBI-v2 to the list of enzymes available from New England BioLabs
- Added fields for username and email address in the license registration dialog
Enhancements:
- Optimized storage of history for the following operations: Change Methylation, Change Transformation Strain, Set Origin, Flip, Insert/Delete/Replace, Linearize, Circularize
- Updated the supported protein feature types by adding new types (NonStdRes, Protein, Precursor, SecStr, Het, CDS, gene, misc_feature, unsure, variation), promoting Region subtypes to types, and adding new Site and Bond subtypes
- Added a note in Features view to indicate the presence of internal stop codons in a translated feature
- Enhanced the Preferences tools to allow more flexible default options for displaying ORFs
- Enabled carrying over feature qualifiers when creating a protein sequence using "Make Protein" or "Reverse Translate"
- Added the option to merge segments when using "Make Protein" on a multi-segment DNA feature
- Added a "Hide noncutters" check box in the Choose Enzymes dialog
- Enabled importing features from any supported file type when using "Import Features from a SnapGene File"
- Enabled more flexible batch conversion of chromatogram traces to other formats
- Improved search performance for large DNA sequences
- Configured the minimap to show both scrolled areas when two copies of Sequence view are visible
- Updated the format of the Preferences dialog, and added an "Agarose Gels" tab
- Added the option to designate a new collection as the Main Collection
- Enabled saving imported online sequences directly to a collection
- Added shortcuts in a collection Overview for navigating to the DNA Files, Protein Files, or Miscellaneous Files sections
- Enabled symbols to be entered in search queries when searching SnapGene Online Sequences
- Increased the size of the length indicator in the map label at the "Small" font size
- Consolidated all Fisher MW Markers for agarose gels in the Fisher Scientific set
- Configured the Nonredundant Commercial enzyme set to include similar enzymes that differ by methylation sensitivity
- Configured SnapGene to show the Launch dialog on macOS when the SnapGene icon in the Dock is clicked, if no SnapGene windows are open
- Changed the icon for enabling interrupted circle format for a linear DNA sequence in Map view
- Configured the "Export Map" and "Export History" options to be always enabled
- Improved the wording of various menu options and dialogs to provide greater clarity and consistency
- Added a message informing the user that files can be dragged into the list when using Align Multiple Sequences
Fixed:
- Fixed an issue that prevented cloning dialogs from allowing the use of hidden enzymes
- Corrected an issue in "Protein Search" whereby terminal stop codons were not included in the search query
- Ensured that edits in an alignment window do not cause inappropriate scrolling
- Corrected an issue that could prevent alignment of a high-quality sequence trace
- Ensured that the "Find" control in the Enzymes view chooser always shows a message to indicate if the enzyme is not in the chosen set
- Corrected an issue in which U's in overhangs resulting from linearizing were not preserved
- Configured "Select All" in the trace viewer context menu to actually select all
- Ensured that History view reflects changes after editing DNA ends
- Ensured that case changes in the "Find" entry field are preserved when the search is executed
- Ensured that imported RNA alignments are converted to DNA rather than protein alignments
- Corrected the license inactivity countdown to displays seconds rather than milliseconds
- Ensured that the "Accession Number:" label remains next to its entry field in the collection Search dialog
- Ensured that a "Sequence Name" search in the Protein Files area of a collection also searches the map labels and aliases
- Corrected an issue that resulted in alignment and collection windows not showing unsaved changes in the title bar on Windows and Linux
- Ensured more consistent sorting of enzymes in the Choose Enzymes dialog
- Streamlined the substitution matrix options presented when computing pairwise alignments
- Ensured that open alignments can be used as profiles when computing new alignments
- Corrected an issue that could result in the "Kind" column disappearing when viewing a collection
- Ensured that crisp screenshots are shown when detecting updates
- Improved import of the full publication date from PubMed
- Made various stability fixes
更新時間：2020-09-23
更新細節：
What's new in this version:
Fixes:
- Corrected a regression with computing pairwise alignments on Windows and Linux
- Improved reliability when importing from NCBI
更新時間：2020-09-17
更新細節：
What's new in this version:
New Functionality:
- Added Agilent TapeStation ladders
Fixed:
- Corrected a regression that prevented decoding of features in Gene Construction Kit files
- Corrected a regression that prevented the bacterial transformation strain from being applied to the cloning product
- Fixed an issue with applying the "Limit file history" preference
- Improved detection of Gateway attR1, attR2 and attR4 sites
- Improved the default binding site shown when invoking the Edit Primer dialog for a primer with multiple binding sites
- Corrected an issue with simulating Gateway cloning using att sites that lie across the numerical origin
- Removed an outdated comment regarding PmlI losing activity when stored at -20°C
- Corrected the Import Primers dialog to proceed when Enter/Return is pressed
- Fixed an issue that could result in peak data disappearing when editing Sanger sequence traces
- Corrected a regression that prevented Shift-selecting a range of primers in Primers view
- Removed the "Fixed Line Width" button from the side toolbar in the Anneal Oligos dialog
- Corrected various stability issues when using cloning dialogs
- Ensured that the Sequence view minimap is consistently shown
- Fixed an issue with migrating the chosen enzymes when cloning while using a custom local enzyme set
- Corrected a regression that could cause the Browse Common Features dialog to switch from Sequence to Map view when the displayed feature was changed
- Improved the tooltips for history operations
- Ensured that changing the sequence methylation reliably updates the methylation state in the Description Panel
- Improved the document icon for DNA alignments to include a shadow
- Corrected an issue with splitting the view after having previously done so
- Corrected an issue with using Shift and the Left/Right arrow keys to move selected ranges across an entire gap in an alignment
更新時間：2020-07-21
更新細節：
What's new in this version:
New Functionality:
- Added a "Copy Rich Text" command for selections in alignments, to provide the option of copying either simple sequences or sequences with metadata
Enhancements:
- Added Invitrogen's "pScreen-iT LacZ-Dest" to the list of Gateway® Destination vectors
- Modified the statistics in pairwise alignments to show two digits after the decimal point instead of one
- Added time estimates to various progress dialogs
- Improved the order of "Copy" actions in the Edit menu
- Made various textual, alignment, and spacing improvements
- Enabled export of a map or history while viewing any tab
Fixes:
- Ensured reliable import of primers copied to the clipboard using Microsoft Office
- Added support for dragging and dropping FASTA archives into the Assemble Contigs dialog
- Preserved zoom and split view display options when switching between files in a collection
- Enhanced the Gene Construction Kit importer to capture the full set of notes in the "General Info" section
- Improved stability when computing and viewing multiple sequence alignments
- Corrected an issue that could cause features to be erroneously detected around the numerical origin of a linear sequence
- Ensured that proper file extensions were included when batch converting files from one format to another
- Ensured correct setting of the default button in the Find controls when pressing and releasing Shift in a sequence trace window
- Corrected a regression with the navigation buttons when viewing an alignment to a reference sequence
- Addressed issues with the purple bar and the Tm column when importing primers from another file
- Corrected the displayed molecular weight when adding a translated feature to the common features database
- Removed the colors button in cloning dialogs, and streamlined the side toolbar in the Edit DNA Ends, Browse Common Features, and Mutageneis dialogs
- Improved the display of long sequence names within circular maps
- Corrected a regression by removing cut locations for ancestral restriction sites in History view
- Removed the inappropriate "Preserve feature annotations" control from the New File dialog, and the inappropriate "Detect common features" control when inserting or replacing bases in a sequence trace window
- Improved stability when assembling contigs using FASTQ data
- Disabled the Show/Hide All Enzymes commands when viewing protein files
- Corrected an issue in which the endpoints of a selection were not updated in the selection bar after renumbering the origin of a linear sequence
- Fixed an issue that prevented immediately using SnapGene without restarting after activating a Flexera-based shared license
- Corrected an issue with computing % GC when partially degenerate residues (B, D, H, and V) were present
- Ensured that only the zoomed region is shown for the root map in History view
- Addressed an issue in which the Save As dialog would vanish immediately when attempting to choose a different name instead of saving over an existing file
- Ensured that enzyme set menus are refreshed after using Manage Enzyme Sets
- Ensured that the desired endpoint modifications are correctly applied when designing a synthetic construct
- Improved the registration of file associations on macOS
更新時間：2020-06-20
更新細節：
更新時間：2020-06-18
更新細節：
What's new in this version:
New Functionality:
- Added support for importing protein features from the GFF3 format
- Enabled features to be preserved when a replacement leaves the sequence length unchanged
Enhancements:
- Enabled the import of custom user fields from Vector NTI databases
- Increased the 3' match length limit to 25 bases when importing primers from a list
- Enabled capture of the history of a protein translated from DNA when importing from Vector NTI Advance
- Enhanced primer tooltips to include % GC for the annealed region
- Improved copy and paste of sequence alignments into text editors and other programs
- Increased the size of the DOI field when editing references
- Made various color, layout, and textual enhancements
Fixes:
- Mandated use of the proper default font size when creating new files, importing from online, and opening non-native files
- Corrected an issue that prevented importing primers into multiple files in a collection
- Corrected a regression with displaying translations and the "Original Sequence" when no sequences are aligned to the reference DNA sequence
- Enabled changing methylation for placeholder files
- Fixed various issues when working with placeholder files
- Implemented automatic correction of invalid alignments to a reference sequence computed with prior versions
- Fixed an issue that prevented manually specifying the zoomed range
- Corrected the "+" symbol in plasmid names when importing from "SnapGene Online Sequences"
- Ensured correct updating of the zoomed range when navigating to matches with the Find tool
- Addressed an issue with specifying the position of protein interchain bond locations
- Removed the "Codons" cascading menu when interacting with protein sequences
- Corrected an issue that prevented importing multi-sequence GenBank and GenPept files into a collection
- Ensured that translation numbering is maintained when using Make Protein from multiple selected translated features
- Ensured that the match threshold controls are listed only once when importing features from a SnapGene file
- Corrected an issue that could cause file names to be clipped in source menus
- Fixed an issue that caused files to be marked as modified after hovering over hyperlinks in the Description Panel
- Ensured that stop codons present in protein query strings are included in the search results
- Improved the import of multi-part qualifiers from Geneious
- Fixed an issue with undo of sequence color changes that are limited to a single strand
- Corrected the "Copy" shortcut when viewing a protein sequence or multi-protein alignment
- Ensured more robust behavior when adding primers to DNA sequences
- Turned on the display of truncated primer description data when full descriptions are toggled off in Primers view
- Corrected an issue in which simplified primer binding sites were not shown after modifying hybridization parameters
- Ensured that sufficient space is always allocated above displays of complex primer binding sites in Sequence view
- Turned on display of the parental enzyme set when viewing Nicking Endonucleases in Sequence and Map views
- Improved reliability when importing from Addgene
- Improved the import of Addgene sequences that contain slashes in their names
- Ensured that side toolbar buttons in dialogs are not hidden
- Corrected a regression in which two copies of common features such as EGFP were sometimes annotated when detecting common features
- Removed "Match Threshold" controls from the "Add to Common Features" dialog
更新時間：2020-06-16
更新細節：
更新時間：2020-06-16
更新細節：
What's new in this version:
Access:
- rtp descriptor leak on error fix
Demux:
- Fixed regression with some encrypted HLS streams
- Live HLS delay until first update fix
- HLS rendition switch regression fix
- Fix imprecise m4a seek
Decoder:
- Fixed missing captions with some capture cards
Audio filters:
- soxr resampling fixes
Contribs:
- Updated libfaad to 2.9.2 (Parametric Stereo regression)
- Updated libarchive to 3.4.2
Audio Output:
- Fix sound not coming back after a pause with CoreAudio (macOS/iOS)
Misc:
- Update Youtube script