P53 oncogene

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P53 oncogene

2019年12月11日 — The key role of p53 as a tumor suppressor became clear when it was realized that this gene is mutated in 50% of human sporadic cancers, and ... ,It was initially presumed to be an oncogene due to the use of mutated cDNA following purification of tumor cell mRNA. Its role as a tumor suppressor gene was ... ,Why Was p53 Originally Believed to Be an Oncogene? A variety of studies carried out with the protein, and later with the gene encoding p53, indicated ... ,2019年8月20日 — So, the early conclusions were not entirely wrong: p53 can indeed be oncogenic, but only as a consequence of mutations within its coding region. ,... Oncogenes*; Phosphoproteins / genetics*; Phosphoproteins / metabolism; Sequence Homology, Nucleic Acid; Tumor Suppressor Protein p53; Viral Proteins / ... ,Oncogenes are mutant alleles of proto-oncogenes. Through their mutation they have acquired novel or aberrant properties that promote cell transformation. ,2015年5月29日 — The standard classification used to define the various cancer genes confines tumor protein p53 (TP53) to the role of a tumor suppressor gene. ,The standard classification used to define the various cancer genes confines tumor protein p53 (TP53) to the role of a tumor suppressor gene. However, it is now ... ,2015年5月29日 — Abstract. The standard classification used to define the various cancer genes confines tumor protein p53 (TP53) to the role of a tumor suppressor ... ,2016年9月13日 — TP53是一種腫瘤抑制基因,透過基因轉錄及轉譯出來具有功能性的蛋白質為p53。p53是由393個胺基酸組成,由4個部分組成(domain)各別有不同 ...

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P53 oncogene 相關參考資料
Do Mutations Turn p53 into an Oncogene? - NCBI - NIH

2019年12月11日 — The key role of p53 as a tumor suppressor became clear when it was realized that this gene is mutated in 50% of human sporadic cancers, and ...

https://www.ncbi.nlm.nih.gov

p53 - Wikipedia

It was initially presumed to be an oncogene due to the use of mutated cDNA following purification of tumor cell mRNA. Its role as a tumor suppressor gene was ...

https://en.wikipedia.org

p53, Cancer | Learn Science at Scitable - Nature

Why Was p53 Originally Believed to Be an Oncogene? A variety of studies carried out with the protein, and later with the gene encoding p53, indicated ...

https://www.nature.com

p53: not just a tumor suppressor | Journal of Molecular Cell ...

2019年8月20日 — So, the early conclusions were not entirely wrong: p53 can indeed be oncogenic, but only as a consequence of mutations within its coding region.

https://academic.oup.com

p53: oncogene or anti-oncogene? - PubMed

... Oncogenes*; Phosphoproteins / genetics*; Phosphoproteins / metabolism; Sequence Homology, Nucleic Acid; Tumor Suppressor Protein p53; Viral Proteins / ...

https://pubmed.ncbi.nlm.nih.go

p53: Oncogene, Tumor Suppressor, or Both? | SpringerLink

Oncogenes are mutant alleles of proto-oncogenes. Through their mutation they have acquired novel or aberrant properties that promote cell transformation.

https://link.springer.com

TP53: an oncogene in disguise - NCBI - NIH

2015年5月29日 — The standard classification used to define the various cancer genes confines tumor protein p53 (TP53) to the role of a tumor suppressor gene.

https://www.ncbi.nlm.nih.gov

TP53: an oncogene in disguise - PubMed

The standard classification used to define the various cancer genes confines tumor protein p53 (TP53) to the role of a tumor suppressor gene. However, it is now ...

https://pubmed.ncbi.nlm.nih.go

TP53: an oncogene in disguise | Cell Death & Differentiation

2015年5月29日 — Abstract. The standard classification used to define the various cancer genes confines tumor protein p53 (TP53) to the role of a tumor suppressor ...

https://www.nature.com

後天基因:致癌基因(oncogene)還是抑癌基因(tumor ... - 基因叔叔

2016年9月13日 — TP53是一種腫瘤抑制基因,透過基因轉錄及轉譯出來具有功能性的蛋白質為p53。p53是由393個胺基酸組成,由4個部分組成(domain)各別有不同 ...

https://unclegene6666.pixnet.n