Aminoglycoside mechanism of action

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Aminoglycoside mechanism of action

,由 KM Krause 著作 · 2016 · 被引用 1027 次 — Aminoglycosides are potent, broad-spectrum antibiotics that act through inhibition of protein synthesis. The class has been a cornerstone of antibacterial ... ,由 LP Kotra 著作 · 2000 · 被引用 786 次 — The presence of the aminohydroxybutyryl group in general prevents the enzymatic modification of amikacin at multiple positions. This antibiotic undergoes ... ,Mechanisms of action. Aminoglycosides display concentration-dependent bactericidal activity against most gram-negative aerobic and facultative anaerobic ... ,Aminoglycosides are broad spectrum antibiotics with potent activity mediated through inhibition of protein synthesis. This class of antibiotic was a fundamental ... ,由 AW Serio 著作 · 2017 · 被引用 36 次 — The general mechanism of action of aminoglycosides is inhibition of protein synthesis by promotion of mistranslation and elimination of ... ,Hence, aminoglycosides have both immediate bactericidal effects through membrane disruption and delayed bactericidal effects through impaired protein synthesis; ... ,Aminoglycosides have concentration-dependent bactericidal activity. These antibiotics bind to the 30S ribosome, thereby inhibiting bacterial protein ... ,由 KM Krause 著作 · 2016 · 被引用 1021 次 — MECHANISM OF ACTION. Aminoglycosides inhibit protein synthesis by binding, with high affinity, to the A-site on the 16S ribosomal RNA of the 30S ribosome (Kotra ... ,由 S Rivetti 著作 · 2023 · 被引用 3 次 — Aminoglycosides take effect by interacting with the 30S subunit of bacterial ribosome. They bind to the base pairs C1409-G1491 at the A-site of bacterial 16S ...

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Aminoglycoside mechanism of action 相關參考資料
Aminoglycosides - UpToDate

https://www.uptodate.com

Aminoglycosides: An Overview - PMC

由 KM Krause 著作 · 2016 · 被引用 1027 次 — Aminoglycosides are potent, broad-spectrum antibiotics that act through inhibition of protein synthesis. The class has been a cornerstone of antibacterial .....

https://www.ncbi.nlm.nih.gov

Aminoglycosides: Perspectives on Mechanisms of Action ...

由 LP Kotra 著作 · 2000 · 被引用 786 次 — The presence of the aminohydroxybutyryl group in general prevents the enzymatic modification of amikacin at multiple positions. This antibiotic undergoes ...

https://www.ncbi.nlm.nih.gov

Aminoglycoside

Mechanisms of action. Aminoglycosides display concentration-dependent bactericidal activity against most gram-negative aerobic and facultative anaerobic ...

https://en.wikipedia.org

Aminoglycoside - an overview

Aminoglycosides are broad spectrum antibiotics with potent activity mediated through inhibition of protein synthesis. This class of antibiotic was a fundamental ...

https://www.sciencedirect.com

Aminoglycosides: Mechanisms of Action and Resistance

由 AW Serio 著作 · 2017 · 被引用 36 次 — The general mechanism of action of aminoglycosides is inhibition of protein synthesis by promotion of mistranslation and elimination of ...

https://link.springer.com

Gentamicin: Uses, Interactions, Mechanism of Action - DrugBank

Hence, aminoglycosides have both immediate bactericidal effects through membrane disruption and delayed bactericidal effects through impaired protein synthesis; ...

https://go.drugbank.com

Aminoglycosides - MSD Manual Professional Edition

Aminoglycosides have concentration-dependent bactericidal activity. These antibiotics bind to the 30S ribosome, thereby inhibiting bacterial protein ...

https://www.msdmanuals.com

Aminoglycosides: An Overview

由 KM Krause 著作 · 2016 · 被引用 1021 次 — MECHANISM OF ACTION. Aminoglycosides inhibit protein synthesis by binding, with high affinity, to the A-site on the 16S ribosomal RNA of the 30S ribosome (Ko...

https://perspectivesinmedicine

Aminoglycosides-Related Ototoxicity: Mechanisms, Risk ...

由 S Rivetti 著作 · 2023 · 被引用 3 次 — Aminoglycosides take effect by interacting with the 30S subunit of bacterial ribosome. They bind to the base pairs C1409-G1491 at the A-site of bacterial 16S .....

https://www.mdpi.com