MAME (32-bit)

What's new in this version:

New:
- New Golden Gate Assembly simulation tool, either using existing Type IIS enzymes or through automated primer and overhang desig
- New Secondary Structure view tab for single stranded RNA sequences. Structures calculated using the ViennaRNA packag
- Added support for Dark mode, automatically using the OS settings for macOS and Window
- Native support for Apple Silicon machine
- Enabled customization of content exported to GenBank including LOCUS field identifier and feature export options

Enhanced:
- Added "Synthetic Protein" and "Unknown" options for the Source attribute in the description pane
- Added DNA ladders from OriGen
- Ladder fragment lengths are now displayed in the fragment list in agarose gel
- Added LOBSTR to the list of E. coli strain
- Improved the detection and simplified the display of primer hybridizations with 3' overhang
- Provide a cancel option when a message is shown indicating an unknown or not installed custom feature type must be addressed before proceeding with editing or duplicating one or more feature
- Added links to SnapGene Academ
- Extensive optimization
- Various textual and layout enhancements

Fixed:
- Improved stabilit
- Fixed various memory leak
- Fixed issues with opening some GenBank file
- Ensured the fragment list in cloning dialogs continue to refresh when either enzyme is manually cleare
- Improved text spacing after punctuation characters on macO
- Fixed an issue that prevented the Enzymes view "Select Range" context menu command from workin
- Improved mouse pointer shape when over links in Collection window
- Fixed or improved various links to SnapGene.com page
- Fixed an issue where cloning dialogs could get stuck generating the produc
- Fixed an issue where some windows omitted the title bar on Window
- Fixed an issue where selected codons were not always shown using a white foreground in Sequence vie
- Fixed an issue where Ready to Clone was still shown after adding or removing a fragment, even if cloning was no longer possibl
- Use the default file format specified in Preferences when exporting alignment
- Fixed an issue with Geneious file import where features in protein sequences could erronously be translate
- Fixed an issue with Geneious file import where introns in nucleotide sequences imported were translate
- Fixed an issue where the Enter key in the numpad was not responsive when a combo box or line edit had focus on macO
- Improved image quality when exporting to EMF forma
- Improved display of checkboxes on Window
- Fixed dropdown menus in Windows which sometimes had clipped tex
- Fixed issues with the display and behaviour of default buttons in dialog
- Fixed an issue with files appearing disabled in the macOS file explorer when they were able to be chose
- Fixed an issue that prevented pasting into the Find control in the Open and Save As dialogs on macO
- Fixed an issue that prevented importing AddGene sequences that contain reserved characters in the file name into a Collection on Window
- Corrected an issue that resulted in an incredibly wide window when importing a database from CSV format that lacks headers into a Collectio
- Fixed an issue where ancestral sequences that cannot be resurrected were shown as blue links in the text format of History vie
- Fixed an issue where the Add Primer command could add a primer to an open DNA window even if a Collection window was active when the command was triggere
- Fixed an issue with the display of an amino acid selection highlighting within a translatio
- Fixed an issue on Ubuntu whereby AB1 files in a Collection opened in SnapGene Viewer if installe
- Fixed some issues with dialogs opening in strange positions, such as on a different monito
- Addressed a stability issue when editing a collection description
- Fixed an issue with importing mixed content types from NCB
- Fixed various issues with the sequence name when importing from NCBI, especially when using the COMPLEMENT operator
- Fixed a number of printing issues on Windows when the operating system is set to scale all content to 100% or 150%
- Fixed the appreance of the transformation strand menu in the Change Methylation dialog on Windows
- Fixed printing the header for multiple sequence alignments on Windows using 100-200% scaling
- Improved printing margins on Windows
- Improved print quality of mutiple sequence alignments on Windows
- Imporved the default height of the Insert Codons dialog
- Improved the horizontal alignment of text in the fragmnets list shown in Agarose Gel documents
- Improved the display of site feature labels in multiple sequence alignemnts
- Fixed an issue where browsed or edited common features are not realible shown with all relevant qualifiers in the Browse Common Features dialog
- Repliably respect the "Detect either an exact protein match or approximate DNA match" setting when detecting common features
- Improved margins when printing on Window
- Fixed horizontal alignment of enzyme names when printing on Windows
- Addressed various issues when printing on Windows with the display scaling set to 200% or higher
- Improved the width of spinboxes on Windows
- Avoid elliding menu commands on Window
- Fixed various issues that made it difficult to install software updates on Windows
- Improved behavior of progress bar when when installing software updates on macOS